RB1 Antibody (RB1/1754), Alexa Fluor™ 750, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP254476AF750

Catalog No. NP24476A70

Description

RB1 Monoclonal specifically detects RB1 in Human, Mouse samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: RB1
• Classification: Monoclonal
• Conjugate: Alexa Fluor 750
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Symbols: RB1
• Immunogen: Recombinant human RB1 protein (Uniprot: P06400)
• Primary or Secondary: Primary
• Test Specificity: Recognizes a 105kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It reacts with the hyper-phosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
• Content And Storage: Store at 4°C in the dark.

• Applications: Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
• Clone: RB1/1754
• Dilution: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
• Gene Alias: OSRC, osteosarcoma, p105-Rb, pp110, pRb, Rb, retinoblastoma 1, retinoblastoma suspectibility protein, retinoblastoma-associated protein
• Host Species: Mouse
• Quantity: 0.1 mL
• Gene ID (Entrez): 5925
• Target Species: Human, Mouse
• Isotype: IgG1 κ