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RB1 (phospho T826) Rabbit anti-Human, Mouse, Rabbit, Polyclonal , Abnova™

Catalog No. 89956789 Shop All Abnova Corporation Products
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89-956-789 100 μL
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Catalog No. 89-956-789 Supplier Abnova Corporation Supplier No. PAB29632
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human RB1.

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq]

Specifications

Antigen RB1 (phospho T826)
Applications Immunofluorescence, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human RB1.
Dilution Immunofluorescence (1:100-1:200) Western Blot (1:500-1:3000) The optimal working dilution should be determined by the end user.
Formulation In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Alias OSRC/RB/p105-Rb/pRb/pp110
Gene Symbols RB1
Host Species Rabbit
Immunogen A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T826 of human RB1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5925
Test Specificity RB1 (phospho T826) polyclonal antibody detects endogenous level of RB1 only when phosphorylated at threonine 826.
Target Species Human, Mouse, Rabbit
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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