RB1 Polyclonal Antibody, Active Motif™

Catalog No.	Quantity
50-199-3522	100 μL
50-199-3523	10 μL

Catalog No. 50-199-3522 Supplier Active Motif Supplier No. 61585

Description

Rabbit Polyclonal Antibody

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

Specifications

• Antigen: RB1
• Applications: Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: Lot-Specific
• Conjugate: Unconjugated
• Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
• Gene: RB1
• Gene Accession No.: P06400
• Gene Alias: Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; Rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; Retinoblastoma 1 (including osteosarcoma); retinoblastoma protein; retinoblastoma suspectibility protein; Retinoblastoma-associated protein
• Gene Symbols: RB1
• Host Species: Rabbit
• Immunogen: This antibody was raised against a peptide within the C-terminal region of human RB1.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5925
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG