RB1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-5988	150 μL

Catalog No. 50-172-5988 Supplier Proteintech Group Inc Supplier No. 100482IG150UL

Description

Rabbit Polyclonal Antibody

This antibody is a rabbit polyclonal antibody raised against human RB1 fusion protein.

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia. Phosphorylation of Rb at S608 depends on CDK4.

Specifications

• Antigen: RB1
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: RB1
• Gene Accession No.: P06400, P13405
• Gene Alias: OSRC, p105 Rb, pp110, pRb, RB, RB1, retinoblastoma 1
• Gene Symbols: RB1
• Host Species: Rabbit
• Immunogen: RB1 Fusion Protein Ag0006
• Purification Method: Protein A
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 19645, 5925
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG