Invitrogen™ RbAp46 Recombinant Rabbit Monoclonal Antibody (3L1H6)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA551387

Catalog No. FEMA551387

Description

Immunogen sequence: MASKEMFEDT VEERVINEEY KIWKKNTPFL YDLVMTHALQ WPSLTVQWLP EVTKPEGKDY ALHWLVLGTH TSDEQNHLVV ARVHIPNDDA QFDASHCDSD KGEFGGFGSV TGKIECEIKI NHEGEVNRAR YMPQNPHIIA TKTPSSDVLV FDYTKHPAKP DPSGECNPDL RLRGHQKEGY GLSWNSNLSG HLLSASDDHT VCLWDINAGP KEGKIVDAKA IFTGHSAVVE.

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation.

Specifications

• Antigen: RbAp46
• Classification: Recombinant Monoclonal
• Concentration: 0.26 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q16576, Q60973, Q71UF4
• Gene Symbols: RBBP7
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human RbAp46/RBBP7 (NP_002884.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Format: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 3L1H6
• Conjugate: Unconjugated
• Gene: RBBP7
• Gene Alias: AA409861; AI173248; AU019541; BB114024; G1/S transition control protein-binding protein; G1/S transition control protein-binding protein RbAp46; histone acetyltransferase type B subunit 2; Histone-binding protein RBBP7; mRbAp46; Nucleosome-remodeling factor subunit RBAP46; RB binding protein 7, chromatin remodeling factor; Rbap46; Rbbp7; RBBP-7; retinoblastoma binding protein 7; retinoblastoma-binding protein 7; Retinoblastoma-binding protein p46; retinoblastoma-binding protein RbAp46
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 245688, 5931, 83712
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid
• Isotype: IgG