Invitrogen™ RBBP5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121050

Catalog No. PIPA5121050

Description

Positive test controls include: MCF7, NCI-H460, HeLa, Mouse spleen, Mouse brain, Mouse thymus, Rat liver. The target is usually found in the following locations: Nucleus. Immunogen sequence: SIWAQNQVEN WSAFAPDFKE LDENVEYEER ESEFDIEDED KSEPEQTGAD AAEDEEVDVT SVDPIAAFCS SDEELEDSKA LLYLPIAPEV EDPEENPYGP PPDAVQTSLM DEGASSEKKR QSSADGSQPP KKKPKTTNIE LQGVPNDEVH PLLGVKGDGK SKKKQAGRPK GSKGKEKDSP FKPKLYKGDR GLPLEGSAKG KVQAELSQPL TAGGAISELL.

This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Specifications

• Antigen: RBBP5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rbbp5
• Gene Alias: 4933411J24Rik; C330016J05; RB binding protein 5, histone lysine methyltransferase complex subunit; RBBP 5; Rbbp5; RBBP-5; RBQ 3; RBQ3; retinoblastoma binding protein 5; retinoblastoma-binding protein 5; Retinoblastoma-binding protein RBQ-3; SWD1; SWD1, Set1c WD40 repeat protein, homolog
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 213464, 304794, 5929
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.54 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q15291, Q8BX09
• Gene Symbols: Rbbp5
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 319-538 of human RBBP5 (NP_005048.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG