Invitrogen™ RBBP6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559697

Catalog No. PIPA559697

Description

Immunogen sequence: KATYDTKRPN EETKSVDKNP CKDREKHVLE ARNNKESSGN KLLYILNPPE TQVEKEQITG QIDKSTVKPK PQLSHSSRLS SDLTRETDEA AFEPD Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 75%.

This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

Specifications

• Antigen: RBBP6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rbbp6
• Gene Alias: 4933422O15Rik; AI316869; BB233631; C030034J04Rik; C77662; E3 ubiquitin-protein ligase RBBP6; im:7158869; MY038; my038-like; P2PR; P2P-R; p53-associated cellular protein of testis; PACT; Proliferation potential-related protein; protein P2P-R; RB binding protein 6, ubiquitin ligase; RB-binding Q-protein 1; Rbbp6; rbbp6l; RBQ1; RBQ-1; retinoblastoma binding protein 6; retinoblastoma-binding protein 6; retinoblastoma-binding protein 6, isoform 3; retinoblastoma-binding Q protein 1; RING-type E3 ubiquitin transferase RBBP6; SNAMA
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5930
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q7Z6E9
• Gene Symbols: Rbbp6
• Immunogen: Recombinant protein corresponding to Human RBBP6. Recombinant protein control fragment (Product #RP-102914).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG