Invitrogen™ RBBP6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542292

Catalog No. PIPA542292

Description

Peptide sequence: NYDTVTFDGL HISLCDLKKQ IMGREKLKAA DCDLQITNAQ TKEEYTDDNA Sequence homology: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%.

This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

Specifications

• Antigen: RBBP6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rbbp6
• Gene Alias: 4933422O15Rik; AI316869; BB233631; C030034J04Rik; C77662; E3 ubiquitin-protein ligase RBBP6; im:7158869; MY038; my038-like; P2PR; P2P-R; p53-associated cellular protein of testis; PACT; Proliferation potential-related protein; protein P2P-R; RB binding protein 6, ubiquitin ligase; RB-binding Q-protein 1; Rbbp6; rbbp6l; RBQ1; RBQ-1; retinoblastoma binding protein 6; retinoblastoma-binding protein 6; retinoblastoma-binding protein 6, isoform 3; retinoblastoma-binding Q protein 1; RING-type E3 ubiquitin transferase RBBP6; SNAMA
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5930
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q7Z6E9
• Gene Symbols: Rbbp6
• Immunogen: Synthetic peptide directed towards the N-terminal of human RBBP6 (aa 13-62).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov