Invitrogen™ RBFOX1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559307

Catalog No. PIPA559307

Description

Immunogen sequence: PAEYTAPHPH PAPEYTGQTT VPEHTLNLYP PAQTHSEQSP ADTSAQTVSG TATQTDDAAP TDGQPQTQPS E Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.

Specifications

• Antigen: RBFOX1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rbfox1
• Gene Alias: 2BP1; A FOX-1; A2BP; A2BP1; ataxin 2 binding protein 1; ataxin 2-binding protein 1; ataxin-2-binding protein 1; FOX1; fox-1; fox-1 homolog A; fox-1-like RNA-binding protein 1; hexaribonucleotide binding protein 1; hexaribonucleotide binding protein 1 isoform alpha; hexaribonucleotide binding protein 1 isoform beta; hexaribonucleotide-binding protein 1; HRNBP1; MNCb-3035; RBFOX1; RNA binding fox-1 homolog 1; RNA binding protein fox-1 homolog 1; RNA binding protein, fox-1 homolog (C. elegans) 1; RNA binding protein, fox-1 homolog 1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54715
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.10 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NWB1
• Gene Symbols: Rbfox1
• Immunogen: Recombinant protein corresponding to Human RBFOX1. Recombinant protein control fragment (Product #RP-98674).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG