Invitrogen™ RBFOX2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113686

Catalog No. PIPA5113686

Description

Immunogen sequence: STQAHGEQSS NSPSTQNGSL TTEGGAQTDG QQSQTQSSEN SESKSTPKRL For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%.

This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: RBFOX2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RBFOX2
• Gene Alias: dJ106I20.3; Fbm2; fox-1 homolog B; Fox-1 homolog Fxh; fox-1 homologue; FOX2; Fox-2; Fxh; Fyn-binding molecule 2; hexaribonucleotide-binding protein 2; HNRBP2; Hrnbp2; Rbfox2; Rbm9; repressor of tamoxifen transcriptional activity; RNA binding fox-1 homolog 2; RNA binding motif protein 9; RNA binding protein fox-1 homolog 2; RNA binding protein fox-1 homolog 2; RNA binding protein, fox-1 homolog (C. elegans) 2; RNA binding protein, fox-1 homolog (C. elegans) 2; RNA binding protein, fox-1 homolog 2; RNA-binding motif protein 9; RNA-binding protein 9; RTA; zgc:85694
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23543
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O43251
• Gene Symbols: RBFOX2
• Immunogen: Synthetic peptide directed towards the N terminal region of human RBM9 (aa 74-123).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov