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Invitrogen™ RBM11 Polyclonal Antibody
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Catalog No. PIPA531249
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100 μL
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Catalog No. Quantity
PIPA531249 100 μL
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Catalog No. PIPA531249 Supplier Invitrogen™ Supplier No. PA531249
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: NT2D1, IMR32, U87-MG. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The RBM11 (RNA Binding Motif Protein 11) gene encodes a protein that belongs to a family of RNA-binding proteins involved in the regulation of alternative splicing, a critical process for generating protein diversity. Located on chromosome 21q22.3, RBM11 contains RNA recognition motifs (RRMs) that facilitate its binding to RNA sequences, influencing splice site selection and exon inclusion or exclusion during pre-mRNA processing. RBM11 is expressed in various tissues, with notable expression in the nervous system, suggesting a role in neural development and function. Dysregulation of RBM11 has been associated with various diseases, including cancer, where it can impact the splicing of key regulatory genes involved in cell proliferation and apoptosis. Understanding the specific RNA targets and splicing events regulated by RBM11 can provide insights into its broader biological roles and its potential as a biomarker or therapeutic target in diseases characterized by aberrant splicing.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RBM11
Applications Western Blot
Classification Polyclonal
Concentration 0.56 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Rbm11
Gene Accession No. P57052
Gene Alias A330018F01; putative RNA-binding protein 11; Rbm11; RNA binding motif protein 11; RNA-binding motif protein 11; Splicing regulator RBM11
Gene Symbols Rbm11
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human RBM11. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54033
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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