Invitrogen™ RBM15 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA592321

Catalog No. PIPA592321

Description

Immunogen sequence: EHRYQQQYLQ PLPLTHYELV TDAFGHRAPD PLRGARDRTP PLLYRDRDRD LYPDSDWVPP PPPVRERSTR TAATSVPAYE PLDSLDRRRD GWSLDRDRGD RDLPSSRDQP RKRRLPEESG GRHLDRSPES DRPRKRHCAP SPDRSPELSS SRDRYNSDND RSSRLLLERP SPIRDRRGSL EKSQGDKRDR KNSASAERDR KHRTTAPTEG KSPLKKEDRS DGSAPSTSTA SSKLKSPSQK QDGGTAPVAS A; Positive Samples: HL-60, HepG2, 293T, Jurkat, Mouse thymus, Mouse spleen; Cellular Location: Nucleus, Nucleus membrane, Nucleus speckle, Peripheral membrane protein, nucleoplasm.

May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.

Specifications

• Antigen: RBM15
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RBM15
• Gene Alias: C230088J01Rik; Kiaa4257; mKIAA1438; one twenty two protein; one twenty-two; one-twenty two protein 1; OTT; OTT1; putative RNA-binding protein 15; RBM15; RNA binding motif protein 15; RNA-binding motif protein 15; RNA-binding protein 15; SPEN
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 229700, 64783
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.38 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q96T37
• Gene Symbols: RBM15
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 530-780 of human RBM15 (NP_0011884741).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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