RBM28 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-0978	150 μL

Catalog No. 50-173-0978 Supplier Proteintech Group Inc Supplier No. 164841AP150UL

Description

Rabbit Polyclonal Antibody

Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes. Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments. The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With VAPA, may regulate ER morphology. Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion. Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3. Also binds 25-hydroxycholesterol and cholesterol.

Specifications

• Antigen: RBM28
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Polyclonal
• Concentration: 0.15 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: RBM28
• Gene Accession No.: Q8CGC6, Q9NW13
• Gene Alias: RBM28, RNA binding motif protein 28, RNA binding protein 28
• Gene Symbols: RBM28
• Host Species: Rabbit
• Immunogen: RBM28 Fusion Protein Ag9606
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 312182, 55131, 68272
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG