Invitrogen™ RBM5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA535963

Catalog No. PIPA535963

Description

Recommended positive controls: K562, THP-1. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (80%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similar expression patterns. Both DEF-3 and LUCA15 are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the haemopoietic system of mice, the expression of DEF-3 is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both DEF-3 and LUCA15 contain two zinc finger motifs, a bipartite nuclear signal and two RNA binding motifs. DEF-3 and LUCA15 are capable of specifically binding poly(G) RNA.

Specifications

• Antigen: RBM5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RBM5
• Gene Alias: D030069N10Rik; G15; H37; LUCA15; Protein G15; Putative tumor suppressor LUCA15; Rbm5; Renal carcinoma antigen NY-REN-9; RMB5; RNA binding motif protein 5; RNA-binding motif protein 5; RNA-binding protein 5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10181
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P52756
• Gene Symbols: RBM5
• Immunogen: Recombinant fragment corresponding to a region within amino acids 715 and 815 of RBM5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov