Invitrogen™ RBM6 Monoclonal Antibody (3E9)

Catalog No.	Quantity
PIMA520951	100 μg

Catalog No. PIMA520951 Supplier Invitrogen™ Supplier No. MA520951

Description

Mouse Monoclonal Antibody

Peptide Sequence: DSPERKRIKY SRETDSDRKL VDKEDIDTSS KGGCVQQATG WRKGTGLGYG HPGLASSEEA EGRMRGPSVG ASGRTSKRQS NETYRDAVRR VMFARYKELD.

DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similar expression patterns. Both DEF-3 and LUCA15 are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the haemopoietic system of mice, the expression of DEF-3 is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both DEF-3 and LUCA15 contain two zinc finger motifs, a bipartite nuclear signal and two RNA binding motifs. DEF-3 and LUCA15 are capable of specifically binding poly(G) RNA.

Specifications

• Antigen: RBM6
• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Monoclonal
• Clone: 3E9
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.4
• Gene: RBM6
• Gene Accession No.: P78332
• Gene Alias: 3G2; 4930506F14Rik; DEF3; DEF-3; ETK2; g16; HEK2; HLC-11; Lung cancer antigen NY-LU-12; lung cancer protooncogene 11; mKIAA4015; NY-LU-12; Protein G16; Rbm6; RGD1560367; RNA binding motif protein 6; RNA-binding motif protein 6; RNA-binding protein 6; RNA-binding protein DEF-3; TYRO6
• Gene Symbols: RBM6
• Host Species: Mouse
• Immunogen: RBM6 (NP_005768.1, 1024 a.a. ~ 1123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10180
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a κ