Invitrogen™ RBM6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587864

Catalog No. PIPA587864

Description

Immunogen sequence: TLEYVSSLDF WYCKRCKANI GGHRSSCSFC KNPREVTEAK QELITYPQPQ KTSIPAPLEK QPNQPLRPAD KEPEPRKREE GQESRLGHQK REAERYLPPS RREGPTFRRD RERESWSGET RQDGESKTIM LKRIYRSTPP EVIVEVLEPY VRLTTANVRI IKNRTGPMGH TYGFIDLDSH AEALRVVKIL QNLDPPFSID GKMVAVNLAT GKRRNDSGDH SDHMHYYQGK KYFRDRRGGG R; Positive Samples: A-549, 293T, HeLa, HepG2; Cellular Location: Nucleus.

DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similar expression patterns. Both DEF-3 and LUCA15 are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the haemopoietic system of mice, the expression of DEF-3 is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both DEF-3 and LUCA15 contain two zinc finger motifs, a bipartite nuclear signal and two RNA binding motifs. DEF-3 and LUCA15 are capable of specifically binding poly(G) RNA.

Specifications

• Antigen: RBM6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RBM6
• Gene Alias: 3G2; 4930506F14Rik; DEF3; DEF-3; ETK2; g16; HEK2; HLC-11; Lung cancer antigen NY-LU-12; lung cancer protooncogene 11; mKIAA4015; NY-LU-12; Protein G16; Rbm6; RGD1560367; RNA binding motif protein 6; RNA-binding motif protein 6; RNA-binding protein 6; RNA-binding protein DEF-3; TYRO6
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10180
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P78332
• Gene Symbols: RBM6
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 530-770 of human RBM6 (NP_0057681).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov