Invitrogen™ RBM8A Monoclonal Antibody (4C4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA536288

Catalog No. PIMA536288

Description

Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Western blot detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa).

This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.

Specifications

• Antigen: RBM8A
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q9DF42, Q9Y5S9
• Gene Symbols: RBM8A, rbm8a.S
• Immunogen: Full length native protein (purified) (Human).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Frog
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Western Blot
• Clone: 4C4
• Conjugate: Unconjugated
• Gene: RBM8A
• Gene Alias: 2310057C03Rik; AA673428; Binder of OVCA1-1; BOV1; BOV-1; BOV1A; BOV-1A; BOV1B; BOV-1B; BOV1C; BOV-1C; C1DELq21.1; DEL1q21.1; fb34f03; HSPC114; MDS014; Rbm8; RBM8A; rbm8-A; rbm8a.S; rbm8a-A; rbm8a-b; RBM8B; ribonucleoprotein RBM8; ribonucleoprotein RBM8A; Ribonucleoprotein RBM8A-A; RNA binding motif protein 8; RNA binding motif protein 8A; RNA binding motif protein 8A S homeolog; RNA binding motif protein 8B; rna-binding; RNA-binding motif protein 8A; RNA-binding motif protein 8A-A; RNA-binding protein 8A; RNA-binding protein 8A-A; RNA-binding protein Y14; TAR; tsunagi; Unknown (protein for MGC:127566); wu:fb34f03; XELAEV_18042903mg; Y14; zgc:110525; ZNRP; zrnp1
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 399167, 9939
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid