Invitrogen™ RBMXL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA541848

Catalog No. PIPA541848

Description

Peptide sequence: SSRDGYSSRD YREPRGFAPS PGEYTHRDYG HSSVRDDCPL RGYSDRDGYG Sequence homology: Cow: 85%; Dog: 77%; Guinea Pig: 77%; Horse: 77%; Human: 100%; Mouse: 77%; Rabbit: 85%; Rat: 85%.

The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. RBMXL2 has two RRM domains that bind RNAs. RBMXL2 has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).

Specifications

• Antigen: RBMXL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RBMXL2
• Gene Alias: 1700012H05Rik; Heterogeneous nuclear ribonucleoprotein G; heterogeneous nuclear ribonucleoprotein G T; hnRNP G; hnRNP G-T; HNRNPGT; Hnrnpg-t; HNRPG; HNRPGT; LOC617969 protein; NEWGENE_1598286; RBMX; RBMX like 2; Rbmxl2; RNA binding motif protein, X-linked like 2; RNA binding motif protein, X-linked-like 2; RNA-binding motif protein, X chromosome; RNA-binding motif protein, X chromosome, N-terminally processed; RNA-binding motif protein, X-linked-like-2; testes specific heterogenous nuclear ribonucleoprotein G T; testes-specific heterogenous nuclear ribonucleoprotein G-T; testis-specific heterogeneous nuclear ribonucleoprotein G-T
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27288
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O75526
• Gene Symbols: RBMXL2
• Immunogen: Synthetic peptide directed towards the middle region of human RBMXL2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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