Invitrogen™ RBP1 Monoclonal Antibody (G4E4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA135782

Catalog No. 01-672-086

Description

G4E4 recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.

This gene encodes the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: RBP1
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P02696, P09455, Q00915
• Gene Symbols: Rbp1
• Immunogen: Human retinol binding protein (RBP) purified from plasma.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Rabbit, Monkey, Goat
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Clone: G4E4
• Conjugate: Unconjugated
• Gene: Rbp1
• Gene Alias: C CRABP-I; cellular retinol binding protein 1; Cellular retinol-binding protein; Cellular retinol-binding protein I; CRABP-I; CRBP; CRBP1; Crbpi; CRBP-I; LOW QUALITY PROTEIN: retinol-binding protein 1; mCRBPI; RBP; RBP1; Rbp-1; RBPC; retinol; retinol binding; Retinol Binding Protein; retinol binding protein 1; retinol binding protein 1, cellular; retinol-binding protein 1; retinol-binding protein 1, cellular
• Host Species: Mouse
• Purification Method: purified
• Regulatory Status: RUO
• Gene ID (Entrez): 100354448, 102189996, 19659, 25056, 5947
• Content And Storage: 4°C
• Form: Liquid