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RBP2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 188251AP

Catalog No. 50-173-2244


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Description

Description

UPF3B is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The protein is one of two functional homologs to yeast Upf3p. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctionsThis gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene.
Specifications

Specifications

RBP2
0.24 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P29375, Q3UXZ9
Histone demethylase JARID1A, JARID1A, KDM5A, lysine (K) demethylase 5A, Lysine specific demethylase 5A, RBBP 2, RBBP2, RBP2
Rabbit
IgG
150 μL
-20°C
Primary
214899, 312678, 5927
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
KDM5A
Liquid
Kdm5a
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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