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Invitrogen™ RCC1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA528063
Description
Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji, Neuro2A, GL261. Predicted reactivity: Mouse (94%), Rat (93%), Dog (96%), Rabbit (95%), Chimpanzee (99%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
Specifications
RCC1 | |
Polyclonal | |
Unconjugated | |
RCC1 | |
4931417M11Rik; AI326872; Cell cycle regulatory protein; chc1; chc1-a; chromosome condensation 1; chromosome condensation protein 1; fj77f08; guanine nucleotide-releasing protein; RanGEF; RCC1; rcc1.L; rcc1-a; rcc1-b; RCC1-I; Regulator of chromosome condensation; regulator of chromosome condensation 1; regulator of chromosome condensation 1 L homeolog; SNHG3-RCC1; SNHG3-RCC1 readthrough; wu:fj77f08; XELAEV_18012073mg; xrcc1; zgc:65796; zgc:77114 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
100088, 1104 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1 mg/mL | |
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
P18754, Q8VE37 | |
RCC1 | |
Recombinant fragment corresponding to a region within amino acids 2 and 421 of Human RCC1. | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
Safety and Handling
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