Invitrogen™ RCC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529722

Catalog No. PIPA529722

Description

Recommended positive controls: 293T, A431, Raji. Predicted reactivity: Mouse (93%), Rat (93%), Xenopus laevis (81%), Dog (96%), Rabbit (96%), Chimpanzee (100%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

Specifications

• Antigen: RCC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RCC1
• Gene Alias: 4931417M11Rik; AI326872; Cell cycle regulatory protein; chc1; chc1-a; chromosome condensation 1; chromosome condensation protein 1; fj77f08; guanine nucleotide-releasing protein; RanGEF; RCC1; rcc1.L; rcc1-a; rcc1-b; RCC1-I; Regulator of chromosome condensation; regulator of chromosome condensation 1; regulator of chromosome condensation 1 L homeolog; SNHG3-RCC1; SNHG3-RCC1 readthrough; wu:fj77f08; XELAEV_18012073mg; xrcc1; zgc:65796; zgc:77114
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1104
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P18754
• Gene Symbols: RCC1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 226 of Human RCC1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov