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Invitrogen™ RCCD1 Polyclonal Antibody
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Catalog No. PIPA5110283
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100 μL
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PIPA5110283 100 μL
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Catalog No. PIPA5110283 Supplier Invitrogen™ Supplier No. PA5110283
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DIYIWGWNES GQLALPTRNL AEDGETVARE ATELNEDGSQ VKRTGGAEDG APAPFIAVQP FPALLDLPMG SDAVKASCGS RHTAVVTRTG ELYTWGWGKY GQLGHEDTTS LDRPRRVEYF VDKQLQVKAV T.

Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8 (PubMed:24981860). Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation (PubMed:24981860). Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8 (PubMed:28455245).
TRUSTED_SUSTAINABILITY

Specifications

Antigen RCCD1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.14 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene RCCD1
Gene Accession No. A6NED2
Gene Alias RCC1 domain containing 1; RCC1 domain-containing protein 1; RCCD1
Gene Symbols RCCD1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 230-360 of human RCCD1 (NP_001017919.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 308760, 91433
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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