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RCH1/KPNA2 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

$151.31 - $568.26

Specifications

Antigen RCH1/KPNA2
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Form Liquid
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-157-1670
Encompass_Preferred
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Bethyl Laboratories, Inc
IHC00201T
10 μL
Each for $151.31
Only null left
Add to Cart
 
50-157-1669
Encompass_Preferred
View Documents
Bethyl Laboratories, Inc
IHC00201
100 μL
Each for $568.26
Only null left
Add to Cart
 
Description

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Orangutan and Chimpanzee

Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA2 is the alpha subunit 2 of karyopherin, which forms a complex with importin subunit beta-1 and functions as a cargo carrier that transports various complexes from cytoplasm into nucleus. It is ubiquitously expressed and contains an IBB/importin beta domain, ten Armadillo repeats that bind "cargo" and three intervening nuclear localization sequences (NLSs). It has recently been reported to play an important role in tumorigenesis and tumor progression.
Specifications

Specifications

RCH1/KPNA2
Polyclonal
Liquid
RUO
TBS with 0.1% BSA and 0.09% sodium azide
IPOA1, QIP2, RCH1, SRP1alpha
Between 475 and C-term
Primary
4° C
KPNA2
Immunohistochemistry
Unconjugated
Rabbit
Human, Mouse
P52292, P52293
16647, 3838
IgG
Antigen affinity chromatography
Antibody
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SDS
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Documents

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