Invitrogen™ RCN1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587992

Catalog No. PIPA587992

Description

Immunogen sequence: KPTVRKERVV RPDSELGERP PEDNQSFQYD HEAFLGKEDS KTFDQLTPDE SKERLGKIVD RIDNDGDGFV TTEELKTWIK RVQKRYIFDN VAKVWKDYDR DKDDKISWEE YKQATYGYYL GNPAEFHDSS DHHTFKKMLP RDERRFKAAD LNGDLTATRE EFTAFLHPEE FEHMKEIVVL ETLEDIDKNG DGFVDQDEYI ADMFSHEENG PEPDWVLSER EQFNEFRDLN KDGKLDKDEI RHWILPQDYD HAQAEARHLV YESDKNKDEK LTKEEILENW NMFVGSQATN YGEDLTKNHD EL; Positive Samples: A-549, SKOV3, LO2, HeLa; Cellular Location: Endoplasmic reticulum lumen.

Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.

Specifications

• Antigen: RCN1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RCN1
• Gene Alias: epididymis secretory protein Li 84; FLJ37041; HEL-S-84; PIG20; proliferation-inducing gene 20; Rca1; RCAL; Rcn; RCN1; reticulocalbin 1; reticulocalbin 1, EF-hand calcium binding domain; reticulocalbin-1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19672, 5954
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 3.21 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q05186, Q15293
• Gene Symbols: RCN1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-331 of human RCN1 (NP_0028921).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov