Invitrogen™ RCN3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA598793

Catalog No. PIPA598793

Description

RCN3 Polyclonal Antibody for Western Blot, IHC (P), ELISA

Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum (PubMed:16433634, PubMed:28939891). Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3. By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis. Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens (PubMed:28939891). This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion (PubMed:16433634). [UniProt].

Specifications

• Antigen: RCN3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RCN3
• Gene Alias: 6030455P07Rik; D530026G20Rik; D7Ertd671e; EF-hand calcium-binding protein RLP49; Rcn3; reticulocabin; reticulocalbin 3; reticulocalbin 3, EF-hand calcium binding domain; reticulocalbin-3; RLP49; UNQ239/PRO272
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 52377, 57333
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q8BH97, Q96D15
• Gene Symbols: RCN3
• Immunogen: Recombinant Human Reticulocalbin-3 protein (71-161AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov