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RD1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987568
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100 μL
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50-198-7568 100 μL
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Catalog No. 50-198-7568 Supplier Bioss Supplier No. BS6877R
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Rabbit Polyclonal Antibody

Tis7, also known as IFRD1, is a 442 amino acid containing membrane associated, non-nuclear intracellular protein belonging to the IFRD family. A regulatory protein expressed in a variety of tissues, Tis7 is known to play an important role in the regulation of gene activity in the proliferative and/or differentiative pathways induced by NGF. Reports suggest that Tis7 may be an autocrine factor that attenuates or amplifies the initial ligand induced signal and might also augment the adaptive response by stimulating the production of differentiated enterocytes. Tis7 acts as a negative regulator of transcriptional activity and represses expression of genes involved in myogenesis, muscle maintenance, and regeneration in a histone deacetylase dependent manner.

Specifications

Antigen RD1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene IFRD1
Gene Accession No. O00458
Gene Alias 12-O-tetradecanoylphorbol-13-acetate-induced sequence 7; BOS_4228; Ifnl; Ifrd1; interferon related developmental regulator 1; Interferon-related developmental regulator 1; IRPR; Nerve growth factor-inducible protein PC4; Pc4; pheochromocytoma cell-4; Tis7; TIS7 protein; TPA induced sequence 7; TPA-induced sequence 7
Gene Symbols IFRD1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human IFRD1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3475
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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