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Invitrogen™ REA Polyclonal Antibody
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Catalog No. PIPA514132
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400 μL
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Catalog No. Quantity
PIPA514132 400 μL
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Catalog No. PIPA514132 Supplier Invitrogen™ Supplier No. PA514132
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine, chicken and rat based on sequence homology.

PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging.
TRUSTED_SUSTAINABILITY

Specifications

Antigen REA
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene PHB2
Gene Accession No. O35129, Q99623
Gene Alias AU044498; BAP; Bap37; Bap-37; Bcap27; BCAP37; B-cell associated protein; B-cell receptor associated protein 37; B-cell receptor-associated protein 37; B-cell receptor-associated protein BAP37; D-prohibitin; hBAP; MGC117268; p22; phb2; phb2 {ECO:0000250; PNAS-141; prohibitin 2; prohibitin-2; Rea; Repressor of estrogen receptor activity; UniProtKB:Q99623}
Gene Symbols PHB2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 106-134 amino acids from human PHB2.
Purification Method Antigen Affinity Chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11331, 12034
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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