Invitrogen™ REA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA581532

Catalog No. PIPA581532

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human REA/PHB2.

PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging.

Specifications

• Antigen: REA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PHB2
• Gene Alias: AU044498; BAP; Bap37; Bap-37; Bcap27; BCAP37; B-cell associated protein; B-cell receptor associated protein 37; B-cell receptor-associated protein 37; B-cell receptor-associated protein BAP37; D-prohibitin; hBAP; MGC117268; p22; phb2; phb2 {ECO:0000250; PNAS-141; prohibitin 2; prohibitin-2; Rea; Repressor of estrogen receptor activity; UniProtKB:Q99623}
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 11331
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q99623
• Gene Symbols: PHB2
• Immunogen: A synthetic peptide corresponding to the N-terminus of the Human PHB2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov