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R&D Systems™ Recombinant Human ErbB2/Her2 Fc Chimera Protein CF

R&D Systems™ Recombinant Human ErbB2/Her2 Fc Chimera Protein CF blocks anti-ErbB2 mediated inhibition of the SK‑BR‑3 human breast cancer cell line.

Manufacturer:  R&D Systems™ 1129ER01M

Catalog No. 11-29E-R01M


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Description

Description

Measured by its ability to block anti-ErbB2 mediated inhibition of SK-BR-3 human breast cancer cell proliferation. Brodowicz, T. et al. (1997) Int. J. Cancer 73:875. The ED 50 for this effect is 20-80 ng/mL in the presence of 0.6 µg/mL Goat Anti-Human ErbB2/Her2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1129 ).
Specifications

Specifications

NP_004439
Bioactivity
2064
>90%, by SDS-PAGE with silver staining
NS0
<0.10EU per 1μg of the protein by the LAL method.
Recombinant Protein
Human
Bioactivity
Lyophilized from a 0.2μm filtered solution in PBS.
96.8kDa (monomer)
1mg
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
ERBB2
Unconjugated
Reconstitute at 100μg/mL in sterile PBS.
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