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Novus Biologicals™ Recombinant Human MAGE 1 Protein
SDP

Catalog No. NBP1996695U Shop All R&D Systems Products
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NBP1996695U 5 μg
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Catalog No. NBP1996695U Supplier Novus Biologicals™ Supplier No. NBP1996695UG

Description

Highly purified and high bioactivity. Generating reliable and reproducible results.

  • The Recombinant Human MAGE 1 Protein is derived from E. coli
  • Human malignant neoplasms carry rejection antigens that are recognized by the patients autologous, tumor directed and specific, cytolytic, CD8+T lymphocyte clones (CTL).
  • An important group of antigens is coded by the MAGE family of genes.
  • It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs).
  • Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
  • This product is for research use only and is not approved for use in humans or in clinical diagnosis.

Specifications

Concentration 0.1 mg/mL
For Use With (Application) SDS-PAGE
Gene ID (Entrez) 4100
Molecular Weight (g/mol) 38 kDa
Purification Method >90%, by SDS-PAGE
Quantity 5 μg
Source E. coli
Storage Requirements Store at -20 to -80°C. Avoid freeze-thaw cycles.
Gene Symbol MAGEA1
Buffer Sterile filtered in 50 mM Tris-Acetate, pH 7.5, 1 mM EDTA and 20% glycerol
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