R&D Systems™ Recombinant Human Neprilysin-2/MMEL1 Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Enzyme Activity

Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPPGFSAFK(Dnp)-OH (Catalog # ES005 ). The specific activity is >250 pmol/min/μg, as measured under the described conditions.

Specifications

• Accession Number: AAL08942
• For Use With (Application): Enzyme Activity
• Formulation: Supplied as a 0.2 μm filtered solution in Tris, NaCl and ZnCl2.
• Gene ID (Entrez): 79258
• Molecular Weight (g/mol): M.W. (Observed): 99 kDa, reducing conditions; M.W. (theoretical): 82 kDa
• Name: Neprilysin-2/MMEL1
• Quantity: 10 μg
• Source: Mouse myeloma cell line, NS0-derived human Neprilysin-2/MMEL1 protein Gly69-Trp770, with an N-terminal 6-His tag
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20°C to -70°C as supplied. 3 months, -20°C to -70°C under sterile conditions after opening.
• Endotoxin Concentration: <1.0 EU / 1 μg of the protein by the LAL method.
• Gene Alias: EC 3.4.24, EC 3.4.24.11, MELL1, membrane metallo-endopeptidase-like 1, Membrane metallo-endopeptidase-like 2MGC119455, MGC119454, MMEL1, MMEL2, NEP2, NEP2(m), NEPIIMGC119456, Neprilysin II, Neprilysin2, Neprilysin-2, NL2, NL2NL1, SEP, soluble secreted endopeptidase, zinc metallopeptidase
• Gene Symbol: MMEL1
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Purity or Quality Grade: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Protein: Neprilysin-2/MMEL1