R&D Systems™ Recombinant Mouse PD-L2/B7-DC Fc Chimera Protein, CF
Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity
Manufacturer: R&D Systems™ 1022PL01M
DescriptionMeasured by its ability to inhibit anti-CD3-induced proliferation of stimulated mouse T cells. The ED50 for this effect is 1-6 μg/mL.
|>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.|
|Mouse myeloma cell line, NS0-derived mouse PD-L2/B7-DC protein Mouse PD-L2 (Leu20-Arg219) (N-terminus) Accession # Q9WUL5 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)|
|<0.01 EU / 1 µg of the protein by the LAL method.|
|Reconstitute at 400 µg/mL in sterile PBS.|
|Lyophilized from a 0.2 µm filtered solution in PBS.|
|M.W. (Observed): 76 kDa, reducing conditions; M.W. (theoretical): 49 kDa (monomer)|
|Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.|
|B7-DC, bA574F11.2, Btdc, Butyrophilin B7-DC, Butyrophilin-like Protein, CD273, CD273 antigen, CD273PD-1 ligand 2,mgC142240, PD-1-ligand 2, PDCD1L2MGC142238, PDCD1LG2, PDL2, PDL2B7DC, PD-L2PDCD1 ligand 2, programmed cell death 1 ligand 2, Programmed death ligand 2|
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