R&D Systems™ Recombinant Mouse PD-L2/B7-DC Fc Chimera Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated mouse T cells. The ED50 for this effect is 1-6 μg/mL.

Specifications

• Accession Number: Q9WUL5
• Characterization: Bioactivity
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 80380
• Molecular Weight (g/mol): M.W. (Observed): 76 kDa, reducing conditions; M.W. (theoretical): 49 kDa (monomer)
• Quantity: 1 mg
• Source: Mouse myeloma cell line, NS0-derived mouse PD-L2/B7-DC protein Mouse PD-L2 (Leu20-Arg219) (N-terminus) Accession # Q9WUL5 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.01 EU / 1 μg of the protein by the LAL method.
• Gene Alias: B7-DC, bA574F11.2, Btdc, Butyrophilin B7-DC, Butyrophilin-like Protein, CD273, CD273 antigen, CD273PD-1 ligand 2,mgC142240, PD-1-ligand 2, PDCD1L2MGC142238, PDCD1LG2, PDL2, PDL2B7DC, PD-L2PDCD1 ligand 2, programmed cell death 1 ligand 2, Programmed death ligand 2
• Gene Symbol: Pdcd1lg2
• Product Type: Recombinant Protein
• Conjugate: Unconjugated
• Species: Mouse
• Reconstitution: Reconstitute at 400 μg/mL in sterile PBS.
• Purity or Quality Grade: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: PD-L2/B7-DC/PDCD1LG2