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Tocris Bioscience™ RECTAS Catalog No.: 767950

$891.50 / Each of 1

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Tocris Bioscience™ RECTAS

Name: Tocris Bioscience&trade; RECTAS
Brand: Tocris Bioscience&trade;
SKU: 76-795-0
Price: 891.50 USD

Catalog No. 767950

50 mg

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Quantity:

10 mg

50 mg

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Catalog No. 76-795-0

Supplier: Tocris Bioscience™ 7679/50

$891.50 / Each of 1

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Description

IKBKAP pre-mRNA splicing modulator

RECTAS (rectifier of aberrant splicing) is a pre-mRNA splicing modulator of the IKBKAP (inhibitor of κ light polypeptide gene enhancer in B-cells, kinase complex associated protein) gene. It corrects aberrant IKBKAP splicing in vitro in cellular models of familial dysautonomia and in vivo in transgenic mice. In combination with Phenylbutyric acid (Cat. No. 2682), RECTAS rescues PARK7 aberrant splicing and neuronal cell loss in a midbrain organoid model of familial Parkinson's disease. Orally bioavailable and brain penetrant.

Greener Choice Claims

Environmental benefits include:

Ozone-Safe or Safe for the Ozone Layer

Specifications

Chemical Name or Material	2-Chloro-N-(2-furanylmethyl)-7 H-purin-6-amine
CAS	101862-47-9
Quantity	50 mg
Target	DNA, RNA and Protein Synthesis Compounds
Molecular Formula	C₁₀H₈ClN₅O
Purity	0.98

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Tocris Bioscience™ RECTAS

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