Invitrogen™ RED Polyclonal Antibody

Catalog No.	Quantity
PA550988	100 μL

Catalog No. PA550988 Supplier Invitrogen™ Supplier No. PA550988

Description

Rabbit Polyclonal Antibody

IK Polyclonal Antibody detects endogenous levels of IK protein.

Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family and is expressed during embryogenesis and in some malignancies. IMP-3 is expressed in malignant melanoma but not in benign nevi, even when dysplastic features are present; IMP-3 is expressed in a significantly higher proportion of melanomas than Spitz nevi; and IMP-3 is expressed in metastatic melanomas significantly more than in thin melanomas. IMP-3 appears to be involved in the progression of malignant melanoma and may play an important role in the regulation of the biologic behavior of this tumor.

Specifications

• Antigen: RED
• Applications: Immunohistochemistry, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: IK
• Gene Accession No.: Q13123, Q66HG8, Q9Z1M8
• Gene Alias: arginine/glutamic acid/aspartic acid repeat containing protein; chondrosarcoma-associated protein 2; CSA2; Cytokine IK; Cytokine IK factor; IK; IK cytokine; IK cytokine, down-regulator of HLA II; IK factor; MuRED; prer protein; protein Red; Protein RER; RD element; RED; Rer
• Gene Symbols: IK
• Host Species: Rabbit
• Immunogen: Synthesized peptide derived from the C-terminal region of human IK.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 24010, 291659, 3550
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG