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Invitrogen™ RED Polyclonal Antibody
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Catalog No. PIPA532151
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100 μL
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PIPA532151 100 μL
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Catalog No. PIPA532151 Supplier Invitrogen™ Supplier No. PA532151
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, HepG2. Predicted reactivity: Mouse (96%), Rat (96%), Chicken (87%), Rhesus Monkey (98%), Chimpanzee (99%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family and is expressed during embryogenesis and in some malignancies. IMP-3 is expressed in malignant melanoma but not in benign nevi, even when dysplastic features are present; IMP-3 is expressed in a significantly higher proportion of melanomas than Spitz nevi; and IMP-3 is expressed in metastatic melanomas significantly more than in thin melanomas. IMP-3 appears to be involved in the progression of malignant melanoma and may play an important role in the regulation of the biologic behavior of this tumor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RED
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.01 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene IK
Gene Accession No. Q13123
Gene Alias arginine/glutamic acid/aspartic acid repeat containing protein; chondrosarcoma-associated protein 2; CSA2; Cytokine IK; Cytokine IK factor; IK; IK cytokine; IK cytokine, down-regulator of HLA II; IK factor; MuRED; prer protein; protein Red; Protein RER; RD element; RED; Rer
Gene Symbols IK
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human RED. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3550
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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