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REDD1 Mouse anti-Human, Clone: 1G11, Bethyl Laboratories
Mouse Monoclonal Antibody
Supplier: Bethyl Laboratories, Inc A500001AT

Description
The recommended shelf life for this product is 1 year from date of receipt.
RTP801 was initially identified as a gene induced by DNA damage, and later found to also be regulated by other cellular stresses such as hypoxia and glucocorticoid treatment. Recently, RTP801 has been shown to act as a mediator of tuberous sclerosis complex (TSC)-dependent regulation of the mammalian Target of Rapamycin (mTOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle. In response to energy stress, RTP801 inhibits mTOR function, resulting in dephosphorylation of downstream targets such as ribosomal protein S6 kinase 1 and 4EBP1 and decreasing cell growth. Disregulation of RTP801 may thus contribute to human tumorigenesis.Specifications
REDD1 | |
Monoclonal | |
Unconjugated | |
DDIT4 | |
Protein regulated in development and DNA damage response 1; REDD-1; HIF-1 responsive protein RTP801 | |
Mouse | |
Affinity chromatography | |
RUO | |
54541 | |
4° C | |
Liquid |
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot | |
1G11 | |
phosphate, tris citrate with 0.09% sodium azide; pH 7-8 | |
Q9NX09 | |
DDIT4 | |
Human C-Reaction Protein | |
20 μL | |
Primary | |
Human | |
Antibody | |
IgG1 κ |
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