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Reelin Polyclonal Antibody, Invitrogen™

Catalog No. PIPA565442
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100 μL
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PIPA565442 100 μL
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Catalog No. PIPA565442 Supplier Thermo Scientific Supplier No. PA565442
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TFCEPYGPREL ITTGLNTTTA SVLQFSIGSG SCRFSYSDPS IIVLYAKNNS ADWIQLEKIR APSNVSTIIH ILYLPEDAKG ENVQFQWKQE NLRVGEVYE Highest antigen sequence identity to the following orthologs - mouse 90%, rat 94%.

Reelin in an extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Reelin
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RELN
Gene Accession No. P78509
Gene Alias ETL7; extracellular matrix serine protease; LIS2; PRO1598; Reelen; reeler; Reeler protein; Reelin; RELN; Rl
Gene Symbols RELN
Host Species Rabbit
Immunogen Recombinant Human Reelin
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5649
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov

For Research Use Only

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