Invitrogen™ REEP5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106289

Catalog No. PIPA5106289

Description

Antibody detects endogenous levels of total REEP5.

REEP5 (receptor expression-enhancing protein 5), also known as C5orf18, DP1, TB2 or D5S346, is a 189 amino acid multi-pass membrane protein. Thought to promote the functional cell surface expression of olfactory receptors, REEP5 belongs to the DP1 family and is encoded by a gene that maps to chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the parm of chromosome 5 leads to cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Specifications

• Antigen: REEP5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: REEP5
• Gene Alias: AI324241; AU022809; AW495741; C5orf18; D5S346; deleted in polyposis 1; Dp1; DP1/TB2; GP106; polyposis coli region hypothetical protein DP1; polyposis locus protein 1; Polyposis locus protein 1 homolog; Protein TB2; protein TB2 homolog; R74856; receptor accessory protein 5; receptor expression enhancing protein 5; receptor expression-enhancing protein 5; Reep5; TB2; TB2/DP1; Yip2e; YOP1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13476, 364838, 7905
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: B2RZ37, Q00765, Q60870
• Gene Symbols: REEP5
• Immunogen: A synthesized peptide derived from human REEP5(Accession Q00765), corresponding to amino acid residues M1-L49.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov