Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA5102588

Invitrogen™ REG3G Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA5102588
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA5102588 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA5102588 Supplier Invitrogen™ Supplier No. PA5102588
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total REG3G.

REG3G, also known as regenerating islet-derived 3 gamma, is a gene encoding an antimicrobial peptide crucial for maintaining intestinal homeostasis and regulating host-microbiome interactions. The protein produced by REG3G belongs to the C-type lectin family and is primarily expressed in the gut, where it plays a significant role in defending against bacterial infections. REG3G helps maintain gut barrier function and immune responses, acting in collaboration with interleukin 22 (IL-22), which regulates its expression. This gene is downregulated during chronic ethanol exposure, suggesting an influence on susceptibility to alcoholic liver disease. REG3G is also involved in glucose metabolism, with evidence showing that its administration improves glucose tolerance, potentially through actions mediated by its receptor, Extl3. Furthermore, REG3G has been identified as a nociceptor-enriched hormone, which protects against endotoxic shock by modulating both local and systemic immunity. This diverse functionality underscores the gene's importance in immune modulation, gut physiology, and metabolic processes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen REG3G
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene REG3G
Gene Accession No. O09049, P42854, Q6UW15
Gene Alias AI449515; generating islet-derived, mouse homolog 3 gamma; LPPM429; Pancreatitis-associated protein 1B; pancreatitis-associated protein 3; Pancreatitis-associated protein IB; PAP IB; PAP1B; PAP-1B; Pap3; PAPIB; PAPIII; REG III; Reg III-gamma; REG3G; REG3gamma; REG-3gamma; REG-3-gamma; regenerating family member 3 gamma; regenerating gene III; regenerating islet-derived 3 gamma; regenerating islet-derived protein 3 gamma; regenerating islet-derived protein 3-gamma; Regenerating islet-derived protein 3-gamma 15 kDa form; Regenerating islet-derived protein 3-gamma 16.5 kDa form; Regenerating islet-derived protein III-gamma; REG-III; RegIII (gamma); UNQ429; UNQ429/PRO162
Gene Symbols REG3G
Host Species Rabbit
Immunogen A synthesized peptide derived from mouse Reg3g(Accession O09049), corresponding to amino acid residues Q23-G43.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 130120, 19695, 24620
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.