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Invitrogen™ Relaxin 1 Polyclonal Antibody
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Catalog No. PIPA547858
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100 μg
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PIPA547858 100 μg
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Catalog No. PIPA547858 Supplier Invitrogen™ Supplier No. PA547858
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Description

Sheep Polyclonal Antibody

In direct ELISAs, less than 1% cross-reactivity with recombinant human Relaxin-1 is observed. Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds; however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Relaxin 1
Applications Immunohistochemistry (Frozen), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Rln1
Gene Accession No. P47932
Gene Alias bA12D24.3.1; bA12D24.3.2; H1; H1RLX; preprorelaxin; preprorelaxin H1; prorelaxin 1; Prorelaxin H1; RELAX; relaxin 1; Relaxin 1 (H1); Relaxin A chain; Relaxin B chain; relaxin RLXH1; Rln; Rln1; rlx; RLX bA12D24.3.1; RLXH1
Gene Symbols Rln1
Host Species Sheep
Immunogen E. coli-derived recombinant mouse Relaxin-1 Arg23-Arg54 with an N-terminal Met (B chain) and Glu161-Cys185 (A chain).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19773
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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