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Invitrogen™ Relaxin 3 Polyclonal Antibody
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Catalog No. PIPA599868
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100 μL
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PIPA599868 100 μL
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Catalog No. PIPA599868 Supplier Invitrogen™ Supplier No. PA599868
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RLN3.

Relaxin 3 is part of the Relaxin-like peptide family that plays an important neuropeptide signaling role. Relaxin 3 is a ligand for two structurally related G protein-coupled receptors, human Relaxin receptor 3 and Relaxin receptor 4. The greatest levels of Relaxin 3 expression occur in the brain, specifically in the pons/medulla, with highest levels in the pars ventromedialis of the dorsal tegmental nucleus and with lower levels in the hippocampus and olfactory regions. Significant expression is also observed in the spleen, thymus, lung and ovary. Relaxin 3 inhibits Forskolin-stimulated cAMP accumulation in a dose-dependent manner in cells that express Relaxin receptor 3. Acute and repeated administration of Relaxin 3 causes a decrease in levels of the plasma thyroid stimulating hormone, suggesting that Relaxin 3 may play a role in long-term control of food intake.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Relaxin 3
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RLN3
Gene Accession No. Q8WXF3
Gene Alias H3; insl7; insulin-like 7; insulin-like peptide 7; Insulin-like peptide INSL7; M3; PRO20213; Prorelaxin H3; prorelaxin M3; relaxin 3; relaxin-3; Relaxin-3 A chain; Relaxin-3 B chain; RLN3; RXN3; UNQ6188; UNQ6188/PRO20213; ZINS4
Gene Symbols RLN3
Host Species Rabbit
Immunogen A synthesized peptide derived from human RLN3(Accession Q8WXF3), corresponding to amino acid residues R104-C142.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117579
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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