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RENT1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501556775
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20 μl; Unlabeled
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Catalog No.
50-155-6775 20 μl; Unlabeled
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Catalog No. 50-155-6775 Supplier Bethyl Laboratories, Inc Supplier No. A300036AT
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Goat Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.

Specifications

Antigen RENT1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene UPF1
Gene Accession No. Q92900, Q9EPU0
Gene Alias Regulator of nonsense transcripts 1; ATP-dependent helicase RENT1; Nonsense mRNA reducing factor 1; NORF1; Up-frameshift suppressor 1 homolog; hUpf1; RENT1; KIAA0221; UPF1;
Gene Symbols UPF1
Host Species Goat
Immunogen Between 250 and 300
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19704, 5976
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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