RENT1 Goat anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Goat Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A300038A

Catalog No. 50-155-6776

Description

The recommended shelf life for this product is 1 year from date of receipt.

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.

Specifications

• Antigen: RENT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UPF1
• Gene Alias: Regulator of nonsense transcripts 1; ATP-dependent helicase RENT1; Nonsense mRNA reducing factor 1; NORF1; Up-frameshift suppressor 1 homolog; hUpf1; RENT1; KIAA0221; UPF1;
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19704, 5976
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q92900, Q9EPU0
• Gene Symbols: Upf1
• Immunogen: Between 1075 and C-term
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG