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Invitrogen™ REPIN1 Polyclonal Antibody
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Catalog No. PIPA557498
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100 μL
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PIPA557498 100 μL
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Catalog No. PIPA557498 Supplier Invitrogen™ Supplier No. PA557498
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MLERRCRGPL AMGLAQPRLL SGPSQESPQT LGKESRGLRQ QGTSVAQSGA QAPGRAHRCA HCRRHFPGWV ALWLHTRRCQ ARLPLPCPE Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 74%.

Replication initiator 1 (REPIN1) is a gene encoding a zinc-finger protein that plays a critical role in various metabolic processes. Located on chromosome 7 in humans, REPIN1 is prominently expressed in liver and adipose tissues. It is associated with the regulation of body weight and triglyceride levels, as evidenced by its locus within a quantitative trait locus (QTL) related to these metabolic traits. The REPIN1 protein is involved in enhancing DNA bending, which is crucial for replication initiation. Studies have shown that deleting REPIN1 in the liver can lead to improved insulin sensitivity and altered lipid metabolism, with secondary effects on adipose tissue. Additionally, REPIN1 is implicated in iron metabolism and apoptosis regulation, further underscoring its multifaceted role in cellular processes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen REPIN1
Applications ChIP Assay, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene REPIN1
Gene Accession No. Q9BWE0
Gene Alias 60 kDa origin-specific DNA-binding protein; 60 kDa replication initiation region protein; AP4; ATT-binding protein; DHFR oribeta-binding protein RIP60; H_DJ0584D14.12; REPIN1; replication initiation region protein (60kD); replication initiator 1; RIP60; Zfp464; Zinc finger protein 464; zinc finger protein 464 (RIP60); zinc finger protein AP4; ZNF464
Gene Symbols REPIN1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human REPIN1. Recombinant protein control fragment (Product #RP-95769).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29803
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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