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REST Rabbit anti-Human, Rat, Polyclonal, Proteintech
SDP

Catalog No. 50560984 Shop All Proteintech Group Inc Products
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50-560-984 150 μL
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Catalog No. 50-560-984 Supplier Proteintech Group Inc Supplier No. 222421AP150UL
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Description

Rabbit Polyclonal Antibody

Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.

Specifications

Antigen REST
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene REST
Gene Accession No. O54963, Q13127
Gene Alias NRSF, REST, X2 box repressor, XBR
Gene Symbols REST
Host Species Rabbit
Immunogen REST Fusion Protein Ag17707
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5978, 83618
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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