RET Monoclonal Antibody (OTI2B3), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-0814	100 μL

Catalog No. 50-168-0814 Supplier OriGene Supplier No. TA805708

Description

Mouse Monoclonal Antibody

RET is a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases which are cell-surface molecules that transduce signals for cell growth and differentiation. RET plays a crucial role in neural crest development, can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described for RET but their biological validity has not been confirmed.

Specifications

• Antigen: RET
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI2B3
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: RET
• Gene Accession No.: P07949
• Gene Alias: CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1
• Gene Symbols: RET
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 713-1017 of human RET produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5979
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1