Invitrogen™ RFC5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103494

Catalog No. PIPA5103494

Description

Antibody detects endogenous levels of total RFC5.

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Specifications

• Antigen: RFC5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RFC5
• Gene Alias: 2610020K06Rik; 2610209F07Rik; 36.5kDa; 36kDa; A1 36 kDa subunit; activator 1 36 kDa subunit; Activator 1 subunit 5; MGC1155; Recc5; replication factor C (activator 1) 5; replication factor C (activator 1) 5, 36.5kDa; replication factor C 36 kDa subunit; replication factor C 5; replication factor C subunit 5; replication factor c subunit 5-like protein; replication factor C subunit RFC5; replication factor C, 36 kDa; replication factor C, 36-kDa subunit; RF-C 36 kDa subunit; RFC, 36.5 kD subunit; RFC36; Rfc5; rfc5 protein; Unknown (protein for MGC:128229); zgc:110313
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5985, 72151
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P40937, Q9D0F6
• Gene Symbols: RFC5
• Immunogen: A synthesized peptide derived from human RFC5(Accession P40937), corresponding to amino acid residues L71-L121.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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