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Invitrogen™ RFTN1 Polyclonal Antibody
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Catalog No. PIPA537032
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100 μL
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PIPA537032 100 μL
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Catalog No. PIPA537032 Supplier Invitrogen™ Supplier No. PA537032
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 63 kDa. Purity is >95% by SDS-PAGE.

Raftlin, also known as RFTN1 (raftlin, lipid raft linker 1), cell migration-inducing gene 2 protein, PIB10, PIG9 or MIG2, is a 578 amino acid cell membrane protein and lipid anchor that is essential for raft cell assembly and maintenance. A member of the raftlin family, Raftlin modulates B-cell antigen receptor-mediated signaling, TCR signals, and is involved in T cell-mediated immune responses. The gene encoding Raftlin maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RFTN1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Rftn1
Gene Accession No. Q14699, Q6A0D4
Gene Alias 2310015n21rik; AI853526; Cell migration-inducing gene 2 protein; KIAA0084; MIG2; PIB10; PIG9; proliferation-inducing protein 10; proliferation-inducing protein 9; Raftlin; raftlin lipid raft linker 1; raftlin, lipid raft linker 1; raft-linking protein; Rftn1; RGD1310777; RGD1563347
Gene Symbols Rftn1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 475-520 of human Raftlin.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23180, 501095, 76438
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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