RFXANK Monoclonal Antibody (OTI2C6), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA504278

Catalog No. 50-167-5000

Description

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity.

Specifications

• Antigen: RFXANK
• Classification: Monoclonal
• Concentration: 0.72 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O14593
• Gene Symbols: RFXANK
• Immunogen: Full length human recombit protein of human RFXANK produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2C6
• Conjugate: Unconjugated
• Gene: RFXANK
• Gene Alias: ANKRA1, BLS, F14150_1, RFX-B
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8625
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid